Determinants of weaning success in patients with prolonged mechanical ventilation

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Determinants of weaning success in patients with prolonged mechanical ventilation

INTRODUCTION Physiological determinants of weaning success and failure are usually studied in ventilator-supported patients, comparing those who failed a trial of spontaneous breathing with those who tolerated such a trial and were successfully extubated. A major limitation of these studies was that the two groups may be not comparable concerning the severity of the underlying disease and the p...

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Predicting success in weaning from mechanical ventilation.

We identified 65 observational studies of weaning predictors that had been reported in 70 publications. After grouping predictors with similar names but different thresholds, the following predictors met our relevance criteria: heterogeneous populations, 51; COPD patients, 21; and cardiovascular ICU patients, 45. Many variables were of no use in predicting the results of weaning. Moreover, few ...

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Survival and success of weaning from prolonged ventilation.

in this case appears to favour a regional technique. The reasons given for not performing an awake ®breoptic intubation are, at best, dubious. We must remember that what we should do is take the safest option, in the patient's best interest. It is worth drawing attention to a recent editorial in The Royal College of Anaesthetists Bulletin, which claims that there have been three deaths attribut...

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Hypercapnic Ventilatory Response in the Weaning of Patients with Prolonged Mechanical Ventilation

Objective To investigate whether hypercapnic ventilatory response (defined as the ratio of the change in minute ventilation [[Formula: see text]] to the change in end-tidal partial pressure of carbon dioxide [ΔPETCO2 ]) is a predictor of successful weaning in patients with prolonged mechanical ventilation (PMV) and to determine a reference value for clinical use. Methods A hypercapnic challen...

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Weaning unit and prolonged mechanical ventilation after critical illness

Methods We retrospectively reviewed medical records of tracheostomized and clinically stable ICU adults patients who required PMV (> 21 days) and weaning (> 7 days) and were transferred to a WU or a GW over a 8-year period (2007-2014) after critical illness. The study was carried out in two tertiary care university hospitals. Study variables were age, sex, APACHE II score, principal diagnosis, ...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2009

ISSN: 1364-8535

DOI: 10.1186/cc7927